E-ISSN 1658-8223 | ISSN 1658-645X
 

Original Article 


Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients

Naif Al Shahrani.

Abstract
Background: The precise pathogenesis remains not fully understood. However, it is thought to involve an autoimmune process directed against melanocytes. Thyroid disorders and autoimmune thyroid diseases have been shown in some reports to be associated with vitiligo. Additionally, there is limited and conflicting data examining the association of antinuclear antibodies (ANA) with vitiligo.

Methods: We conducted a cross-sectional study among 50 vitiligo patients diagnosed according to established clinical criteria at King Khalid University Hospital, Riyadh from January 2008 through December 2010. Blood samples were obtained from the study participants and were tested for antinuclear antibodies (ANA), thyroid stimulating hormone (TSH) and free thyroxin hormone (T4).

Results: Males represented 62% and the mean age was 28.2±11.0 years. A total of 20 (41.7%) had positive ANA values (titer ≥1:40). The mean TSH level was 2.69±2.17 µIU/mL. The mean free T4 level was 16.40±2.74 pmol/L and all patients were in the normal range (10.3-25.8 pmol/L). There were no statistically significant associations between ANA and age, gender, extent of skin lesion, face inclusion, and free thyroxin levels. On the other hand, positive ANA level had significant association with TSH level (p=0.041). With exception of ANA, TSH level had no statistically significant associations with the above variables.

Conclusions: The results of the current study showed higher prevalence of ANA in vitiligo patients, probably suggesting autoimmune process. The current finding may need to be confirmed in a larger prospective multicentric study before recommending periodic screening of patients with vitiligo for thyroid function and antithyroid antibodies.

Key words: Vitiligo, autoimmune, thyroid disease, antinuclear antibodies


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Naif Al Shahrani
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Naif Al Shahrani. Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. Majmaah J Heal Sci. 2014; 2(1): 33-40. doi:10.12816/0004782


Web Style

Naif Al Shahrani. Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. https://www.mjhs-mu.org/?mno=289907 [Access: December 06, 2023]. doi:10.12816/0004782


AMA (American Medical Association) Style

Naif Al Shahrani. Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. Majmaah J Heal Sci. 2014; 2(1): 33-40. doi:10.12816/0004782



Vancouver/ICMJE Style

Naif Al Shahrani. Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. Majmaah J Heal Sci. (2014), [cited December 06, 2023]; 2(1): 33-40. doi:10.12816/0004782



Harvard Style

Naif Al Shahrani (2014) Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. Majmaah J Heal Sci, 2 (1), 33-40. doi:10.12816/0004782



Turabian Style

Naif Al Shahrani. 2014. Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. Majmaah Journal of Health Sciences, 2 (1), 33-40. doi:10.12816/0004782



Chicago Style

Naif Al Shahrani. "Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients." Majmaah Journal of Health Sciences 2 (2014), 33-40. doi:10.12816/0004782



MLA (The Modern Language Association) Style

Naif Al Shahrani. "Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients." Majmaah Journal of Health Sciences 2.1 (2014), 33-40. Print. doi:10.12816/0004782



APA (American Psychological Association) Style

Naif Al Shahrani (2014) Thyroid Disease and Indicator of Autoimmune Illness Among Vitiligo Patients. Majmaah Journal of Health Sciences, 2 (1), 33-40. doi:10.12816/0004782





Most Viewed Articles
Most Accessed Articles

  • Prevalence and Risk Factors of Hypercholesterolemia in Majmaah, Saudi Arabia
    Khalid El Tohami Medani, Mohammed Abdullah Al Mansour, Elsadig Yousif Mohamed, Fahad Alfhaid, Talal Shakhs Alghamdi, Waqas Sami, Sawsan Mustafa Abdalla, Mansour Khater Al Zahrani
    Majmaah J Heal Sci. 2018; 6(1): 34-41
    » Abstract » doi: 10.5455/mjhs.2018.01.006

  • Physical Therapy Intervention in Post Stroke Shoulder Subluxation: A Narrative Review
    Mazen Alqahtani
    Majmaah J Heal Sci. 2018; 6(1): 48-60
    » Abstract » doi: 10.5455/mjhs.2018.01.008

  • Gentamicin induced neurodegenerative changes in auditory cortex of adult Albino rats
    Rehan M Asad, Moattar R Rizvi, Sami Waqas, Kamran Afzal
    Majmaah J Heal Sci. 2013; 1(1): 11-17
    » Abstract » doi: 10.12816/0004766

  • Parental Knowledge, Attitude and Practice on Antibiotic use for Upper Respiratory Tract Infections in Children
    Khaled Al-Dossari
    Majmaah J Heal Sci. 2013; 1(1): 33-45
    » Abstract » doi: 10.12816/0004769

  • Prevalence of Hypertriglyceridemia in Patients Attending Primary Health Care Centers in Majmaah, Saudi Arabia
    Fahad Alfhaid
    Majmaah J Heal Sci. 2018; 6(1): 10-16
    » Abstract » doi: 10.5455/mjhs.2018.01.003

  • Most Downloaded
    Top Downloaded Articles

  • Medical Waste Management Survey in Primary Health Care Centers, Saudi Arabia
    Eltigani O.M Omer, Ali S. R. Alsubaie
    Majmaah J Heal Sci. 2017; 5(1): 7-22
    » Abstract » doi: 10.5455/mjhs.2017.01.003

  • Wet cupping (Hijama) positively and significantly impacted multiple hematological parameters
    Abdulraheem Alshareef, Ahmad Khalaf Alsaedi, Ahmad Abdulaziz Alnakhli, Abdulrahman Amer Albeladi, Raed Saad AlHejili, Mohammed Siddig Younis
    Majmaah J Heal Sci. 2021; 9(2): 98-112
    » Abstract » doi: 10.5455/mjhs.2021.02.011

  • Prevalence & Perception of CAM Usage in Majmaah, Kingdom of Saudi Arabia
    Syed Yousaf Kazmi, Waqas Sami, Saud Ibnsaut Alharbi, Meshaal almeshaal, Anas Alzahrani, Fahad Alyousif, Osama Alenezi
    Majmaah J Heal Sci. 2018; 6(2): 50-61
    » Abstract » doi: 10.5455/mjhs.2018.02.007

  • Physical Therapy Intervention in Post Stroke Shoulder Subluxation: A Narrative Review
    Mazen Alqahtani
    Majmaah J Heal Sci. 2018; 6(1): 48-60
    » Abstract » doi: 10.5455/mjhs.2018.01.008

  • The “Epidemiological Transmission” and “Double-Burden of Disease”: A Focus on Africa
    Asim Abdelmoneim Hussein
    Majmaah J Heal Sci. 2014; 2(2): 3-11
    » Abstract

  • Most Cited Articles
    Most Cited Articles